R230 Focused-ultrasonicator

SKU
500620
  • Treatment Power: .5–110 W Avg. Incident Power/1.5–450 W PIP
  • Sample Processing Capacity: N/A
  • NGS Sample Volumes: 5 to 200 µl

The R230 Focused-ultrasonicator is the next generation AFA® powered instrument, and the first of the R-Series. The R230 can be fully integrated on many liquid handler platforms.

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Technical SpecificationDescription
Primary ApplicationsBead mixing/pellet resuspension, Compound screening, DNA shearing, Hit validation, Low mass sample extraction: FFPE, tissue, and whole blood, Mammalian cell lysis, Target ID & validation
Treatment Power.5–110 W Avg. Incident Power/1.5–450 W PIP
Part Number500620
Power Requirements100 to 240 VAC 500VA, 50 to 60 Hz
Operating EnvironmentAmbient temperature: 19 °C to 25 °C (66 °F to 77 °F) Relative humidity: 30 to 70%
Operating Temperature5 °C to 40 °C
SafetyComplies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/UL 61010-1:2004 “Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use, Part1: General Requirements
Regulatory LabelingCE, ETL Mark (for Product Safety), WEEE
SonoLab VersionSonoLab 10
Operating SystemMicrosoft Windows 10
WCSWCS 3.0 included
ChillerWCS 3.0 (Chiller and WCS in one unit- included with system purchase)
Sample Processing CapacityN/A
NGS Sample Volumes5 to 200 µl
Recommended Batch SizeUp to 384 Samples
Covaris Consumables8 AFA-TUBE TPX Strip, 8 AFA-TUBE TPX 150 Strip, 8 microTUBE Strip, 96 AFA-TUBE TPX Plate, 96 AFA-TUBE TPX 150 Plate, 96 AFA-TUBE PS Plate, 96 microTUBE Plate, 384 AFA-TUBE PP Plate
Upgrade PotentialNo
Associated AccessoriesAutomation Accessories

Key Features

  • Powered by Adaptive Focused Acoustics® (AFA®)
  • On-deck or on-bench
  • Thermally controlled
  • Automation compatible with integrated RFID
  • Automated water management

Benefits

  • Controlled, non-contact processing
  • Compatible with most liquid handlers
  • Maintains optimal sample integrity
  • Reduced human error
  • User-defined scheduling for system set-up maximizes laboratory efficiency
  • Higher recovery

Quick Guide:

R230 DNA Shearing Protocols

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Quick Guide:

truPREP® Protein 12×8 Strip Kit Mammalian Cells (Lysis, Extraction, Digestion)

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96 microTUBE Plate
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96 AFA-TUBE TPX Plate
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8 AFA-TUBE TPX Strip (12)
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384 AFA-TUBE 5 PP Plate
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384 AFA-TUBE 20 PP Plate
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96 AFA-TUBE TPX 150 Plate
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96 AFA-TUBE PS Plate
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8 AFA-TUBE TPX 150 Strip (12)
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8 microTUBE Strip
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R230 Focused-ultrasonicator

Flyer
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From Tissues to LC-MS-ready Protein Digests: Automated Sample Preparation Enabled by Adaptive Focused Acoustics® (AFA®) Technology

Posters
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Enabling Efficiency with Acoustic Energy: High-throughput DNA Shearing

Brochures
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Generating 3 kb DNA for Long-read Sequencing

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R230 Focused-ultrasonicator Setup & Instruction Manual

Product Inserts and User Manuals
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Covaris Automation Platform Solutions for Pre-analytical Sample Preparation

Brochures
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Covaris-certified Consumable Guide

Brochures
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Automated Clinical Rapid Whole Exome Sequencing with the Covaris R230 Focused-ultrasonicator

Covaris Technical Note with Radboudumc DNA fragmentation is a critical step in the preparation of good quality libraries for next-generation sequencing (NGS). Covaris Adaptive Focused...

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High-Throughput, Low Volume gDNA Extraction from Whole Blood Enabled by Covaris Adaptive Focused Acoustics® (AFA®) and AFA-TUBE™ TPX

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Mechanical Fragmentation of RNA using the Covaris Adaptive Focused Acoustics® (AFA®) Technology for Development of mRNA-based Vaccine and Gene Therapy Platforms

Mechanical Fragmentation of RNA using the Covaris Adaptive Focused Acoustics® (AFA®) Technology for Development of mRNA-based Vaccine and Gene Therapy Platforms Introduction The emergence of...

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Shearing DNA with Confidence: A Robust Method for Generating 3 kb DNA

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Tumor Tissue Evaluation with the Illumina® TruSight™ Oncology 500 (NGS) Assay using the Covaris R230 Focused-ultrasonicator for Clinical Research Studies

Abstract: Next-generation sequencing (NGS) library preparation workflows comprise DNA fragmentation as an essential step. Covaris’ Adaptive Focused Acoustics® (AFA®) Technology enables precise and high-quality data...

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