E220evolution Focused-ultrasonicator

  • Treatment Power: 100 W Avg. Incident Power
  • Sample Processing Capacity: Single Tube
  • NGS Sample Volumes: 15 to 130 µl

The E220evolution enables multi-sample, batch preparation, capable of processing a wide range of sample types and volumes and may be programed to process from 1 to 8 samples in a single batch. When workload increases, the E220evolution can be upgraded to an E220 capable of processing 1-96 samples/run or to an LE220 for high-throughput processing without purchasing a new instrument.

More Information
Technical SpecificationDescription
Primary ApplicationsCell lysis: mammalian, bacterial, yeast, cfDNA Extraction from Plasma, DNA Extraction from Dried Blood Spots, DNA/RNA/Chromatin Shearing, DNA/RNA/Total NA/Protein Extraction from FFPE, Tissue lysis and extraction
Treatment Power100 W Avg. Incident Power
Part Number500429
Power RequirementsE100-120, 200-240 V~ 50-60Hz, 500 VAC
Operating EnvironmentAmbient temperature: 19 °C to 25 °C (66 °F to 77 °F) Relative humidity: 30% to 70%
Operating Temperature0.5 °C to 55.0 °C
SafetyComplies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/UL 61010-1:2004 “Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use, Part1: General Requirements
Regulatory LabelingCE and ETL Mark
SonoLab VersionSonoLab 7
Operating SystemWindows 10
ChillerChiller/heater re-circulating system-Not included, sold separately
Sample Processing CapacitySingle Tube
NGS Sample Volumes15 to 130 µl
Recommended Batch Size1 to 8 Samples
Covaris ConsumablesmicroTUBE 8-strip (rack required)
Upgrade PotentialYes
Associated AccessoriesE220evolution Accessories

Key Features

  • Isothermal processing
  • Non-contact, closed vessel
  • Precisely controlled and adjustable energy delivery
  • Automation ready
  • Multi-sample capability
  • Broad sample volume range


  • No heat damage, higher recovery
  • No cross contamination, no aerosols, no clean up
  • Standardized processes, highly reproducible
  • Integrates into customers’ sample processing workflow
  • Higher productivity, less operator intervention
  • One instrument for multiple applications

Quick Guide:

Quick Guide: DNA Shearing with E220 Focused-ultrasonicator


E220evolution User Manual

Product Inserts and User Manuals

E220 / E220x (E-Series) High Performance Multi-Sample Preparation System




Covaris-certified Consumable Guide