Quick Guide: DNA Shearing with ME220 Focused-ultrasonicator
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ME220 Focused-ultrasonicator
SKU
500506
- Treatment Power: 20 W Avg. Incident Power
- Sample Processing Capacity: Single Tube
- NGS Sample Volumes: 15 to 130 µl
The ME220 Focused-ultrasonicator is the multi-sample, multi-application benchtop sample preparation solution for every lab. Capable of 1 to 8 sample batch processing at the bench-top, this compact, easy-to-use system enables precise and accurate results with AFA-energetics®.
| Technical Specification | Description |
|---|---|
| Primary Applications | Cell lysis: mammalian, bacterial, yeast, cfDNA Extraction from Plasma, DNA Extraction from Dried Blood Spots, DNA/RNA/Chromatin Shearing, DNA/RNA/Total NA/Protein Extraction from FFPE, Tissue lysis and extraction |
| Treatment Power | 20 W Avg. Incident Power |
| Part Number | 500506 |
| Power Requirements | 100-240 VAC 500 VA, 50-60Hz, 5 Amp Slo-Blow Fuse |
| Operating Environment | Ambient temperature: 19 °C to 25 °C (66 °F to 77 °F) Relative humidity: 30% to 70% |
| Operating Temperature | Programmable +6.0 °C to +40.0 °C |
| Safety | Complies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/UL 61010-1:2004 “Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use, Part1: General Requirements |
| Regulatory Labeling | CE, ETL Mark (for Product Safety), WEEE |
| SonoLab Version | SonoLab 8 |
| Operating System | Windows 10 |
| WCS | NA |
| Chiller | Stand-alone benchtop |
| Sample Processing Capacity | Single Tube |
| NGS Sample Volumes | 15 to 130 µl |
| Recommended Batch Size | 1 to 8 Samples |
| Covaris Consumables | microTUBE 8 strip, milliTUBE |
| Upgrade Potential | Yes |
| Associated Accessories | ME220 Accessories |
Key Features
- Isothermal process
- Small, compact footprint
- Non-contact, closed vessel
- Flexible sample processing volume
- Highly reproducible results
- Automatable
- Sample tracking with 2D barcoded consumables
- Operates at 500 kHz (Ultrasonic Range)
- Calibrated to NIST traceable standards
Benefits
- No heat-induced bias, high sample recovery
- Fits on any bench top
- No cross-contamination, aerosols, or clean-up
- 15 μl to 1 ml
- Minimal post-process QC required
- Sample vessels compatible with liquid handling robots
- Traceable sample identification
- Beyond audible range – no discomfort to operators
- Optimized protocols available and transferable