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S220 Focused-ultrasonicator
SKU
500217
- Treatment Power: 100 W Avg. Incident Power
- Sample Processing Capacity: Single Tube
- NGS Sample Volumes: 15 to 130 µl
The S220 Focused-ultrasonicator is a versatile, high power system engineered for pre-analytical sample processing using Covaris’ patented Adaptive Focused Acoustics® (AFA®). Utilizing a spherical acoustic transducer, specifically designed acoustical cuvettes and advanced electronics, AFA delivers controlled energy precisely and accurately to sample volumes from 15 μl to 18 ml.
| Technical Specification | Description |
|---|---|
| Primary Applications | Cell lysis: mammalian, bacterial, yeast, cfDNA Extraction from Plasma, DNA Extraction from Dried Blood Spots, DNA/RNA/Chromatin Shearing, DNA/RNA/Total NA/Protein Extraction from FFPE, Tissue lysis and extraction |
| Treatment Power | 100 W Avg. Incident Power |
| Part Number | 500217 |
| Power Requirements | 100-240 VAC 500 VA, 50-60 Hz |
| Operating Environment | Ambient temperature: 19 °C to 25 °C (66 °F to 77 °F) Relative humidity: 30% to 70% |
| Operating Temperature | 19 °C to 25 °C (66 °F to 77 °F) |
| Safety | Complies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/UL 61010-1:2004 “Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use, Part1: General Requirements" |
| Regulatory Labeling | CE, ETL Mark (for Product Safety), WEEE |
| SonoLab Version | SonoLab 7 |
| Operating System | Windows 10 |
| WCS | Yes |
| Chiller | Chiller Required-Not included, sold separately |
| Sample Processing Capacity | Single Tube |
| NGS Sample Volumes | 15 to 130 µl |
| Recommended Batch Size | NA |
| Covaris Consumables | microTUBE, milliTUBE, miniTUBE, Large volume consumables, Flow cells |
| Upgrade Potential | No |
| Associated Accessories | S220 Accessories |
Key Features
- Continuous Temperature Control
- Non-contact, closed vessel
- Accurate, Precise, and Controlled acoustic energy
- Accommodates a broad sample volume range
- Ultrasonic
Benefits
- No heat damage, higher recovery
- No cross contamination, no aerosols, no clean up
- Processes and protocols are highly reproducible
- Multiple applications are accommodated in a single instrument
- AFA does not require sound-proofing or special precautions
The Yin-Yang of Sample Preparation: Reagent optimization for maximal yield, activity, and preservation of biomarkers using Adaptive Focused Acoustics®(AFA®)
Posters
DownloadRobust pre-analytical sample preparation process preserves the accuracy and fidelity of protein phosphorylation states
Posters
DownloadUniversal Sample Processing Of Multiple Sample Types For Reproducible Proteomic Sample Preparation
Posters
DownloadActive Extraction of Native Proteins from Yeast using Covaris Adaptive Focused Acoustics® (AFA®)
Native protein extraction reagents were tested for total protein yield and preservation of enzymatic activity using a “passive extraction” or an AFA-based “active extraction” method,...
Learn MoreActive paraffin removal from FFPE tissues with Adaptive Focused Acoustics
Covaris developed a method of active paraffin removal from FFPE tissues using AFA technology. AFA treatment is applied to a FFPE sample and paraffin is...
Learn MoreAFA-based Sputum Liquification to Enable Downstream Microbial Analysis
Sputim Liquification
Learn MoreDNA Extraction from FFPE samples with Covaris Focused-ultrasonicators
When an Adaptive Focused Acoustics (AFA) treatment is applied to a FFPE sample to extract DNA, it simultaneously deparaffinizes the sample, emulsifies the paraffin, and...
Learn MoreMicrobiome Sample Preparation: Efficient DNA Extraction and Optional Mechanical Shearing
DNA Extraction
Learn MorePreparation of whole body Caenorhabditis elegans extracts for chromatin immunoprecipitation using the Covaris® S220 Focused-ultrasonicator
This application note provides a sample preparation protocol using the Covaris S220 that can be used by investigators looking to process whole body C. elegans...
Learn More