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        • S220High power, single-tube sample preparation
        • M220The “Scientist Standard” for single tube processing
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        • ME220Compact 1 to 8 sample batch processing
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      • AFA-TubeLaser etched polymer vessel for high-throughput workflows
      • microTUBE Small sample volumes, 130µl or less
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  • Consumables

Consumables – Tubes and Vials

  • AFA-TUBE®
  • microTUBE
  • milliTUBE
  • Other AFA Tubes
  • AFA Process Vessels
  • g-TUBE

Consumables - Tubes and Vials

Covaris tubes come in a variety of types and sizes for sample analysis and processing, largely used with AFA-energetics®. The Covaris Adaptive Focused Acoustics® (AFA®) process employs focused bursts of tunable acoustic energy through a water bath to a small focal zone within the Covaris tube immersed in the bath.
The Covaris tube is a critical component to the success of AFA. The AFA-TUBE®️, microTUBE, milliTUBE and miniTUBE product lines were engineered by Covaris to provide controlled isothermal and repeatable treatment at all power settings.
Fragment Size*Sample VolumeCovaris Products
175 to 1.5 kbp5 to 50 µlAFA-TUBE
150 to 1.5 kbp130 µlmicroTUBE-130
150 to 1.5 kbp55 µlmicroTUBE-50
150 to 1.5 kbp15 µlmicroTUBE-15
6 – 20 kb150 µlg-TUBE
*For validated fragment sizes, refer to the Covaris Focused-ultrasonicator Protocol.

AFA-TUBE®️

A specially designed, laser etched polymer vessel enabling a single-tube workflow with no transfer steps for high-throughput workflows.

microTUBE

Glass tubes specifically engineered for use with Focused-ulrasonicators. Meant for small sample volumes, 130µl or less.

milliTUBE

Optimized for use with Focused-ultrasonicators, available in 1ml or 2ml sample volumes. Ideal for chromatin shearing workflows.

g-TUBE

A single-use tube that shears DNA using a bench-top centrifuge- no AFA involved. DNA shearing fragments 6-20kb.

AFA-Process Vessels

Designed to enable highly efficient, high power, low temperature processing of formulations and drug delivery systems.

Other AFA-TUBE

Sample processing tubes in specialized sizes to support AFA-enabled applications and workflows such as chromatin shearing.

Resources

Protocols
Protocols for AFA-enabled applications on Focused-ultrasonicator and cryoPREP instruments.
LEARN MORE

Product Inserts & User Manuals
Product Inserts and User Manuals for Focused-ultrasonicator and cryoPREP instruments, reagent kits and consumables.
LEARN MORE

Application Notes
Technical notes, application notes and case studies for AFA-enabled applications.
LEARN MORE

FAQs

I notice a fiber inside the microTUBE/milliTUBE. What is the purpose of this fiber, and should I be worried about contamination of my samples from this fiber during treatment?

The fiber inside the tubes serves a dual purpose. The first is providing nucleation sites for inertial cavitation. Cavitation is a process where a bubble in the liquid rapidly collapses creating a microjet that fragments the DNA. The second purpose is to allow for efficient mixing of the sample during processing. The acoustic fiber is thoroughly cleaned during the manufacturing process before being inserted inside the tubes and is free from organic contaminants.

How can I shear genomic DNA into fragment sizes larger than 5 kb?

The single use Covaris g-TUBE can be used to shear DNA into large fragment sizes ranging from 6 kb to 20 kb using a bench top centrifuge. Click here to access the “g-TUBE User Manual” for the current settings required to obtain your desired fragment size, or contact [email protected].

I have an Illumina protocol for creating 400bp fragments that uses T6 round bottom glass tubes. What alternatives are recommended?

Covaris has developed DNA shearing protocols using the microTUBE-500 that generates an equivalent DNA fragment size distribution as the one generated in T6 tubes when processed with AFA-energetics®. These protocols are available for all Covaris focused-ultrasonicators. Click here to find all of our DNA Shearing protocols for the latest information.

VIEW MORE FAQS

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