Covaris cryoPREP consumables are designed for use with cryoPREP Dry Pulverizers. Made of durable polyimide film, the unique tissueTUBE remains flexible at cryogenic temperatures and is available in a variety of sizes and thicknesses for a wide range of tissue processing needs.tissueTUBE: A unique consumable constructed of a strong, flexible polymer used for cryofracturing of biological tissues with various masses.
A unique biomedical device constructed of strong, flexible plastic used for cryofracturing of biological tissues for a range of masses.
Protocols for AFA-enabled applications on Focused-ultrasonicator and cryoPREP instruments.
Product Inserts & User Manuals
Product Inserts and User Manuals for Focused-ultrasonicator and cryoPREP instruments, reagent kits and consumables.
Technical notes, application notes and case studies for AFA-enabled applications.
The tissueTUBEs TT05, TT05M, and TT1 are designed to withstand one impact. If a second impact is required, the extra thick (XT) version of each tissueTUBE is recommended. The extra thick bags can be impacted more than once. After the first impact, carefully inspect the tissueTUBE for punctures, re-freeze in liquid nitrogen, and impact again.
Multiple freeze/thaw cycles are never recommended for extraction of biomolecules. We recommend long-term storage of cryofractured tissues in small aliquots to avoid multiple freeze/thaw cycles.
Once the sample is pulverized, is it mandatory for the sample to be processed immediately, or can it be stored?
No, the sample is not required to go through sample processing immediately. After cryofracturing, tissueTUBE plugs can be used to seal the tissueTUBEs for long-term storage at -80C, or vapor phase liquid nitrogen. Alternatively, the cryofractured tissue can be transferred into cryoTUBES for long-term storage.