E220 Focused-ultrasonicator

SKU
500239
  • Treatment Power: 100 W Avg. Incident Power
  • Sample Processing Capacity: Single tube processing
  • NGS Sample Volumes: 15 to 130 µl

The E220 Focused-ultrasonicator enables multi-sample batch preparation, capable of processing a wide range of sample types and volumes. The E220 may be programed to process from 1 to 96 samples in a single batch.

More Information
Technical SpecificationDescription
Primary ApplicationsCell lysis: mammalian, bacterial, yeast, cfDNA Extraction from Plasma, DNA Extraction from Dried Blood Spots, DNA/RNA/Chromatin Shearing, DNA/RNA/Total NA/Protein Extraction from FFPE, Tissue lysis and extraction
Treatment Power100 W Avg. Incident Power
Part Number500239
Power Requirements100-120, 200-240 V~ 50-60Hz, 500 VAC
Operating EnvironmentAmbient temperature: 19 °C to 25 °C (66 °F to 77 °F) Relative humidity: 30% to 70%
Operating Temperature0.5 °C to 55.0 °C
SafetyComplies with Low Voltage Directive 2006/95/EC. Certified to IEC/EN/UL 61010-1:2004 “Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use, Part1: General Requirements
Regulatory LabelingCE and ETL Mark
SonoLab VersionSonoLab 7
Operating SystemWindows 10
WCSYes
ChillerChiller/heater re-circulating system-Not included,sold separately
Sample Processing CapacitySingle tube processing
NGS Sample Volumes15 to 130 µl
Recommended Batch Size1 to 96 samples
Covaris ConsumablesmicroTUBE 8-strip (rack required), microTUBE 96 plate
Upgrade PotentialNo
Associated AccessoriesE220 Accessories

Key Features

  • Isothermal processing
  • Non-contact, closed vessel
  • Precisely controlled and adjustable energy delivery
  • Automation ready
  • Multi-sample capability
  • Broad sample volume range

Benefits

  • No heat damage, higher recovery
  • No cross contamination, no aerosols, no clean up
  • Standardized processes, highly reproducible
  • Integrates into customers’ sample processing workflow
  • Higher productivity, less operator intervention
  • One instrument for multiple applications

Quick Guide:

DNA miniTUBE – Blue for 220 Series

Download

Quick Guide:

DNA miniTUBE – Clear for 220 Series

Download

Quick Guide:

DNA miniTUBE – Red for 220 Series

Download

Quick Guide:

DNA Shearing Quick Guide: microTUBE-15 with S220/E220 Focused-ultrasonicator.

Download

Quick Guide:

DNA Shearing with microTUBEs (<1.5kb fragments) S220/E220

Download

Quick Guide:

Quick Guide: DNA Shearing with E220 Focused-ultrasonicator .

Download

Quick Guide:

RNA Shearing with M220 and ME220 Focused-ultrasonicators

Download

Quick Guide:

TruSight Tumor 170 DNA Shearing Quick Guide

Download

E and LE-Series User Manual for SonoLab 6.2.4 or later

Product Inserts and User Manuals
Download

Optimizing a Dual Fixation Protocol to Study Protein Complexes Binding to Chromatin in vivo

Posters
Download

E/LE220 Series SonoLab 7 User Manual

Product Inserts and User Manuals
Download

E-series User Manual

Product Inserts and User Manuals
Download

A New Effective Method for the Disruption of Pseudomonas aeruginosa Biofilms Using Adaptive Focused Acoustics™(AFA)

Posters
Download

truCOLLECT®, a novel blood collection, stabilization, and DNA extraction system specifically designed for use in NGS

Posters
Download

E220 / E220x (E-Series) High Performance Multi-Sample Preparation System

Brochures
Download

E220evolution

Brochures
Download

Formulation and Drug Delivery Breakthrough processing for poorly soluble API’s

Brochures
Download

Automated NGS Library Preparation with Beckman Biomek FXP and Covaris E220

Key parameters for high quality library preparation are homogeneity of the library insert size and un-biased fragmentation profile, which is why Covaris AFA technology was...

Learn More

Optimizing a Dual Fixation Protocol to Study Protein Complexes Binding to Chromatin in vivo

This application note provides shearing profiles, evaluates epitope integrity each shearing time and ChIP-qPCR results obtained using single step formaldehyde fixation and dual crosslinking protocol.

Learn More

Streamlined Ultra Low Sample Input and Processing Volume Chromatin Shearing Protocols for Fly Embryos and Mammalian Cell Lines

These protocols have been optimized for both mammalian cell lines and fly embryos and reliably fragment chromatin in low volumes from down to 10,000 mammalian...

Learn More

Transitioning from custom amplicon-based parallel sequencing to hybrid capture-based sequencing in molecular pathology routine diagnostics

Molecular Pahology

Learn More