The Covaris microTUBE is used extensively for DNA shearing for generating deep coverage, unbiased fragments for advanced sequence analysis. The microTUBE was designed to optimize inertial cavitation and focus acoustic energy in small volumes (e.g., 50 ml). The integrated AFA® fiber provides nucleation sites and allows for both uniform and faster sample processing. The microTUBE is made with a special grade of hardened glass for low acoustic impedance.
8 microTUBE-50 AFA Fiber H Slit Strip V2
A specially designed and engineered glass vessel with H Slit septa to optimize DNA Shearing in a 50 μL sample volume with Covaris Focused-ultrasonicators.
8 microTUBE-130 AFA Fiber H Slit Strip V2
A specially designed and engineered glass vessel with H Slit septa to optimize DNA Shearing in a 130 μL sample volume with Covaris Focused-ultrasonicators.
microTUBE Compatibility Guide
microTUBE Features and Benefits
|Isothermal||No heat damage, so sample quality and labile metabolites are preserved|
|Non-contact, closed vessel||No cross contamination, clean-up, or aerosol formation|
|Accurate, Precise, and reproducible||Processes and protocols are highly reproducible delivering exactly the size distribution needed for your application, so you have more DNA exactly the size you need with every experiment|
|Gentle||DNA is undamaged providing higher yields and better sensitivity in all downstream applications|
|Unbiased||Mechanical shearing delivers DNA fragments unbiased by sequence context, GC content, or other factors, providing the best template for all sequencing applications|
|Higher Yield||Delivering sheared DNA of the optimal size for your sequencer, by unbiased, and non-damaging (eg, heat damage), means there is DNA and RNA ready for your library preparation when you shear by AFA in a microTUBE|