Watch On-Demand: FFPE Proteomics and Genomics Workflow — Insights from a Single Tissue Source
What does a complete FFPE proteomics and genomics workflow look like when built on the same extraction platform? Watch this EACR 2026 symposium featuring Covaris, Illumina, and Lund University to see how acoustic-based FFPE extraction supports genomic, methylation, and proteomic analysis from a single, scalable sample preparation approach.
Erik Söderbäck of Covaris opens with an overview of solvent-free FFPE DNA and RNA extraction using Adaptive Focused Acoustics technology, along with Covaris library preparation solutions for whole genome and RNA sequencing. Nadia Sedlyarova of Illumina then introduces the 5Base solution, a conversion chemistry that delivers simultaneous genomic variant calling and methylation profiling from a single FFPE library prep, validated with real-world lung cancer and normal tissue data. The symposium closes with Professor György Markó-Varga of Lund University, who shares findings from a melanoma proteomics study of 1,000 samples, built on one of the world’s largest pathology biobanks, including a first-of-its-kind case study tracing a single individual’s tumor evolution across four metastatic events and multiple countries.
Key Takeaways
• This FFPE proteomics and genomics workflow uses solvent-free acoustic extraction as a common foundation across molecular layers
• The Illumina 5Base solution enables simultaneous genomic variant calling and methylation sequencing from a single FFPE library prep
• Real-world lung cancer and normal tissue data confirm consistent coverage, mapping, and methylation results
• High-throughput FFPE proteomic solubilization enables reproducible analysis across a 1,000-sample melanoma cohort
• A first-of-its-kind longitudinal study tracks tumor evolution across four metastatic events in a single individual