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A Comparison of Active and Passive FFPE DNA Extraction Methods and Effects on Downstream Analysis Metrics
Resource Type: Application Notes
Download PDFA New Effective Method for the Disruption of Pseudomonas aeruginosa Biofilms Using Adaptive Focused Acoustics™(AFA)
Resource Type: Posters
Download PDFA New Workflow for Small Tissue Sample Preparation: Freeze, Fracture, and Extract
Resource Type: Posters
Download PDFA Novel Automated, High Throughput, Plasma Protein Biomarker Enrichment Protocol
Resource Type: Videos
View VideoA Novel Solution to FFPE Extraction Challenges for Downstream Clinical Assays
Resource Type: Videos
View VideoA Paradigm Shift: Desiccated Stabilized Transport System for Viral Specimen Collection
Resource Type: Brochures
Download PDFA Robust and Scalable Workflow for Extraction of DNA, RNA, and Protein from FFPE Tissues
Resource Type: Posters
Download PDFA Robust and Standardized Workflow to Analyze C. albicans Differential Protein Expression using Tandem Mass Tag (TMT)
Resource Type: Application Notes
Download PDFA Robust LC-MS analysis of C. albicans – Differential Protein Expression using AFA focused ultrasonication, SP3 and TMT labelling
Resource Type: Posters
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A Streamlined Workflow to Perform ChIP from FFPE Samples
Resource Type: Application Notes
Download PDFAccurate and Cost-Effective Discovery of Active Gene Regulatory Interactions using Arima-HiChiP
Resource Type: Posters
Download PDFActive Deparaffinization Drives Superior Yields, Quality and Sequencing Coverage from FFPE Tissue Samples
Resource Type: Posters
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Active Extraction of Native Proteins from Yeast using Covaris Adaptive Focused Acoustics® (AFA®)
Resource Type: Application Notes
Download PDFActive organic solvent-free paraffin removal is the key to efficient extraction of NGSquality DNA and RNA from FFPE tissues
Resource Type: Posters
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Active paraffin removal from FFPE tissues with Adaptive Focused Acoustics
Resource Type: Application Notes
Download PDFAdaptive focused acoustic lysis for high-throughput shotgun metagenomics and proximity ligation
Resource Type: Posters
Download PDFAdaptive Focused Acoustics: The One Solution for all shearing needs
Resource Type: Posters
Download PDFAdvanced Toolkits for Multiomics
Resource Type: Posters

AFA ultraCUBE Water Management System USER MANUAL
Resource Type: Product Inserts and User Manuals
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AFA-based Efficient DNA Extraction and Optional Mechanical Shearing from Mycobacteria smegmatis
Resource Type: Application Notes
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AFA-based MALDI Biotyper Sample Preparation for Mycobacteria Colonies
Resource Type: Application Notes
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AFA-based MALDI Biotyper™ Sample Prep for MGIT™ Positive Mycobacteria Cultures
Resource Type: Application Notes
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AFA-based Sputum Liquification to Enable Downstream Microbial Analysis
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AFA-energetics®-Mediated DNA Extraction from Yeast and Bacteria Using Scanning in a Labcyte 384-well Plate
Resource Type: Application Notes
Download PDFAFA-Nanocrystal™ Production: Batch-scale (2mL) Cinnarizine (CNZ) Preparation Protocol
Resource Type: Protocols
Download PDFAFA-Nanocrystal™ Production: Batch-scale (2mL) Felodipine Preparation Protocol
Resource Type: Protocols
Download PDFAFA-Nanocrystal™ Production: Batch-scale (2mL) Indomethacin Preparation Protocol
Resource Type: Protocols
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AFA-Nanoemulsion™ : Rice Bran Oil in Water Continuous Process Stream 2 mL Process Vessel
Resource Type: Protocols
Download PDFAFA-Nanoemulsion™ : Rice Bran Oil in Water Continuous Process Stream 22mL Process Vessel
Resource Type: Protocols
Download PDFAFA-sonication Followed by Modified Protein Aggregation Capture (APAC) Enables Direct, Reproducible and Non-toxic Sample Preparation of FFPE Tissue for Mass Spectrometry-based Proteomics
Resource Type: Application Notes
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AFA-TUBE™ The Family of AFA Consumables Designed for Higher Throughput Automation
Resource Type: Brochures
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Affinity-based Enrichment Analyses of DNA Methylation MCIp, MeDIP, hMeDIP
Resource Type: Application Notes
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Amplicon Shearing Using a Covaris® Focused-ultrasonicator
Resource Type: Application Notes
Download PDFAn Automated High-throughput ChIP-Seq Workflow using Covaris Adaptive Focused Acoustics® (AFA®) System for Accelerated IP
Resource Type: Posters
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An Effect of a Shearing Process on the Re-Sequencing of the Arabidopsis thaliana Genome
Resource Type: Application Notes
Download PDFAn optimized single tube workflow for robust, low input NGS library preparation
Resource Type: Posters
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Analysis of DNA fragments using the Agilent 2100 Bioanalyzer
Resource Type: Application Notes
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Assessing FFPE DNA Quality: The “Illumina FFPE QC Kit” Enables Quantitation of Improvements in FFPE DNA Extraction Technologies
Resource Type: Application Notes
Download PDFAutomated Clinical Rapid Whole Exome Sequencing with the Covaris R230 Focused-ultrasonicator
Resource Type: Application Notes
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Automated NGS Library Construction with Eppendorf epMotion® 5075t/TMX and Covaris® Focused-ultrasonicators
Resource Type: Application Notes
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Automated NGS Library Preparation with Beckman Biomek FXP and Covaris E220
Resource Type: Application Notes
Download PDFAutomated Protein Extraction from Clinical Samples with the Covaris ML230 Focused-ultrasonicator
Resource Type: Application Notes
Download PDFAutomated Sample Preparation Combining Adaptive Focused Acoustics® (AFA®) and Single Pot Solid Phase Sample Preparation (SP3)
Resource Type: Application Notes
Download PDFAutomated Sample Preparation for Reproducible Proteomics in Biology and the Clinic
Resource Type: Videos
View VideoAutomated Single Vessel DNA Sample Standardization, Fragmentation, and Library Prep
Resource Type: Videos
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CH05 Chiller and AFA ultraCUBE Water Hose Replacement Warning
Resource Type: Product Inserts and User Manuals
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Chromatin Interaction Analysis by Paired-End Tag Sequencing – ChIA-PET
Resource Type: Application Notes
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Chromosome Conformation Capture Using Biotinylated Oligos – Capture-C
Resource Type: Application Notes
Download PDFClinical Tumor Tissue Evaluated with Illumina® TruSight™ Oncology 500 (NGS) Assay and Sheared on the Covaris ML230 Focused-ultrasonicator
Resource Type: Application Notes
Download PDFCo-extraction of RNA and DNA by Covaris Adaptive Focused Acoustics® (AFA®) Enables Genome-scale Analysis for Most FFPE Tissues
Resource Type: Videos
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Combining Covaris 96 AFA-TUBE TPX Plate with Swift Biosciences Accel-NGS 2S Kit for an Optimized Single Tube Workflow for Robust, Low Input NGS Library Preparation
Resource Type: Application Notes
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Comprehensive Sample Preparation for Proteins Enabled by AFA® Technology
Resource Type: Posters
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Confidently Profile the Epigenetic Landscape within Archived FFPE Samples using truChIP®
Resource Type: Brochures
Download PDFControl Microplate Dynamics with Covaris AFA Mixing and Dissolution
Resource Type: Posters
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Covaris Automation Platform Solutions for Pre-analytical Sample Preparation
Resource Type: Brochures
Download PDFCovaris cryoPREP® with AFA: Enabling High-resolution Diagnostic Metagenomics
Resource Type: Application Notes
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Covaris DNA shearing guide for the Agilent SureSelect Target Enrichment System©
Resource Type: Application Notes
Download PDFCovaris DNA Shearing Verification Kit (PN 520120)
Resource Type: Product Inserts and User Manuals
Download PDFCovaris DNA Shearing Verification Kit for AFA-TUBE TPX Consumables (PN 520120)
Resource Type: Product Inserts and User Manuals
Download PDFCovaris DNA Shearing Verification Kit for AFA-TUBE® TPX Plate on the R230
Resource Type: Product Inserts and User Manuals
Download PDFCovaris truChIP– the Next Generation Technology for Chromatin Shearing
Resource Type: Posters
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Covaris truSHEAR Mechanical DNA Shearing for NGS Applications
Resource Type: Application Notes
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Covaris truSHEAR™ Precision DNA Shearing Enables Precision Medicine
Resource Type: Brochures
Download PDFCovaris Webinar: Optimizing the Extraction of High Molecular Weight DNA from Tissue
Resource Type: Videos
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CP01 cryoPREP® Manual Dry Pulverizer User Manual
Resource Type: Product Inserts and User Manuals
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Cross-linked Yeast Chromatin shearing on the Covaris E210
Resource Type: Application Notes
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Cross-linked Yeast Chromatin Shearing on the Covaris Focused-ultrasonicator
Resource Type: Application Notes
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cryoPREP® Product Line: The non-contact, rapid, dry pulverization system for biological tissue
Resource Type: Brochures
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Cytosine Conversion-based, Genome-wide and Targeted DNA Methylation Analysis
Resource Type: Application Notes
Download PDFDirect, Reproducible and Non-toxic Sample Preparation of FFPE Tissue for MS-based Proteomics
Resource Type: Videos
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DNA Extraction from FFPE samples with Covaris Focused-ultrasonicators
Resource Type: Application Notes
Download PDFDNA Extraction of Lung Cancer Samples for Advanced Diagnostic Testing
Resource Type: Posters
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DNA Shearing for Next Generation Sequencing (NGS) with the M220 Focused-ultrasonicator
Resource Type: Application Notes
Download PDFDNA Shearing Protocols for Ion Torrent Platforms with the M220 Focused-ultrasonicator
Resource Type: Protocols
Download PDFDNA Shearing Quick Guide: microTUBE-15 with S220/E220 Focused-ultrasonicator.
Resource Type: Protocols
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E220 / E220x (E-Series) High Performance Multi-Sample Preparation System
Resource Type: Brochures
Download PDFE220 & LE220 (-plus, R-plus, Rsc) Setup & Instruction Manual
Resource Type: Product Inserts and User Manuals
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Effective disruption of Pseudomonas aeruginosa biofilms using Adaptive Focused Acoustics® (AFA®)
Resource Type: Application Notes
Download PDFEfficient Sample Preparation with Covaris AFA® Technology Enhances Confidence in Illumina® TruSight™ Oncology 500 Assay
Resource Type: Posters
Download PDFEnabling Efficiency with Acoustic Energy: High-throughput DNA Shearing
Resource Type: Brochures
Download PDFEpigenomics at the Speed of Sound: High-throughput Epigenomic Mapping of Low Cell Input Samples using Acoustic Enhanced Immunoprecipitation
Resource Type: Posters
Download PDFEvaluation of a New Protein Extraction Method Using an Advanced Acoustic Technology for Identification of Filamentous Fungi by MALDI-TOF MS
Resource Type: Posters
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Evaluation of Next Generation Library Preparation using DNA Extracted from Dried Blood Spots using truXTRAC® DBS DNA kit
Resource Type: Application Notes
Download PDFExperienced User Quick Guide: truXTRAC® FFPE total Nucleic Acid Plus Kit – Column
Resource Type: Protocols
Download PDFExperienced User Quick Guide: truXTRAC® FFPE total Nucleic Acid Plus Kit –Magnetic Beads
Resource Type: Protocols
Download PDFExtraction of RNA from Laser-Capture Microdissected Clinical FFPE Samples
Resource Type: Videos
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Five-Minute Ultrasonic Inactivation and Protein Extraction of Mycobacteria for Identification by MALDI-ToF MS
Resource Type: Posters
Download PDFFocused Acoustic Enabled High Quality Extraction of both DNA and RNA and Subsequent Bead Purification from an FFPE Sample
Resource Type: Posters
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Focused-ultrasonicators Standardize Sample Preparation for a Variety of Application Areas
Resource Type: Brochures
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Formaldehyde-Assisted Isolation of Regulatory Elements – FAIRE
Resource Type: Application Notes
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Formulation and Drug Delivery Breakthrough processing for poorly soluble API’s
Resource Type: Brochures
Download PDFFour Minute Mycobacterium sp. Sample Preparation Process for MALDI-TOF Identification
Resource Type: Posters
Download PDFFrom Tissues to LC-MS-ready Protein Digests: Automated Sample Preparation Enabled by Adaptive Focused Acoustics® (AFA®) Technology
Resource Type: Posters
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Hands-off Sample Preparation Workflow for Laser Capture Microdissection (LCM) Samples using Adaptive Focused Acoustics (AFA)
Resource Type: Application Notes
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High Molecular Weight DNA Extraction and Purification from Whole Blood – Fully-automatable and High-Throughput
Resource Type: Posters
Download PDFHigh Molecular Weight DNA Sample and Library Preparation For Long-Read Sequencing Using Clinical Tissue Specimens
Resource Type: Posters
Download PDFHigh Performance Multiplexed Target Enrichment Sequencing from FFPE Tissues
Resource Type: Posters
Download PDFHigh Quality DNA and RNA Extraction and Purification from FFPE Samples with Covaris truXTRAC® FFPE tNA Ultra Kit – Magnetic Beads
Resource Type: Application Notes
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High Throughput nucleic acid fragmentation for High Throughput next-gen sequencing applications
Resource Type: Brochures
Download PDFHigh Throughput processing of Human Cardiomyocytes using Covaris AFA technology
Resource Type: Videos
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High-throughput High Molecular Weight DNA Extraction from Human Tissues for Long-read Sequencing
Resource Type: Posters
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High-Throughput, Low Volume gDNA Extraction from Whole Blood Enabled by Covaris Adaptive Focused Acoustics® (AFA®) and AFA-TUBE® TPX
Resource Type: Application Notes
Download PDFHigh-Throughput, Low Volume gDNA Extraction from Whole Blood Enabled by Covaris Adaptive Focused Acoustics® (AFA®) and AFA-TUBE™ TPX
Resource Type: Application Notes
Download PDFImpact of AFA-energetics™ on Enzymatic Hydrolysis of Proteins
Resource Type: Application Notes
Download PDFIncorporating Covaris Focused-ultrasonication into a Fully Automated Diagnostic NGS Workcell
Resource Type: Videos
View VideoInline Thermocouple for Flow Cell (500384)
Resource Type: Product Inserts and User Manuals
Download PDFKingFisher™ Duo Prime Purification in combination with the truXTRAC® FFPE total NA Kit
Resource Type: Software
Download PDFKingFisher™ Duo Prime Purification in combination with the truXTRAC® FFPE total NA Plus Kit
Resource Type: Software
Download PDFKingFisher™ Duo Prime Purification in combination with the truXTRAC® cfDNA Kit
Resource Type: Protocols
Download PDFLE220 (-plus, R-plus, and Rsc) Setup & Instruction Manual
Resource Type: Product Inserts and User Manuals
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LE220Rsc Focused-ultrasonicator: High-performance, Scalable, Automated Sample Preparation
Resource Type: Brochures
Download PDFLoading and Rebuilding Process Vessel SST 2ml (500350) Using Prep-Station (500345)
Resource Type: Product Inserts and User Manuals
Download PDFLoading and Rebuilding Process Vessel SST 300µl (500328) Using Prep Station (500333)
Resource Type: Product Inserts and User Manuals
Download PDFLoading and unloading Process Vessel SST 2ml (500350) onto Holder Process Vessel SST 2ml (500347)
Resource Type: Product Inserts and User Manuals
Download PDFLoading and unloading Process Vessel SST 300µl (500328) onto Holder Process Vessel SST 300µl (500319)
Resource Type: Product Inserts and User Manuals
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Lysis and Extraction of Biomolecules from Eukaryotic and Prokaryotic Cells Powered by AFA-energetics®
Resource Type: Application Notes
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Lysis and High Molecular Weight DNA Extraction from Eukaryotic and Prokaryotic Cells Powered by AFA-energetics®
Resource Type: Application Notes
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M220 Focused-ultrasonicator Setup & Instruction Manual
Resource Type: Product Inserts and User Manuals
Download PDFMaintaining SonoLab 7 Log and History Files
Resource Type: Product Inserts and User Manuals
Download PDFMeasuring Sodium Dodecyl Sulfate Carryover In Protein Hydrolysates Prepared via Protein Aggregation Capture
Resource Type: Application Notes
Download PDFMechanical Fragmentation of RNA using the Covaris Adaptive Focused Acoustics® (AFA®) Technology for Development of mRNA-based Vaccine and Gene Therapy Platforms
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Microbiome Sample Preparation: Efficient DNA Extraction and Optional Mechanical Shearing
Resource Type: Application Notes
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Microbiome Samples: Reveal the Hidden Diversity Using Adaptive Focused Acoustics® (AFA®)
Resource Type: Brochures
Download PDFmicroTUBE-50 AFA® Fiber Screw-Cap (PN 520166) Product Insert
Resource Type: Product Inserts and User Manuals
Download PDFML230 Focused-ultrasonicator Uninstallation and Packaging Instructions for Return Shipment
Resource Type: Protocols
Download PDFNano-suspension formation via crystallization (Felodipine based)
Resource Type: Protocols
Download PDFNGS Quality Sample Preparation with Covaris Adaptive Focused Acoustics (AFA)
Resource Type: Videos
View VideoNovel, Automated Co-extraction of High-quality DNA and RNA from a Single FFPE Sample
Resource Type: Posters
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Nucleic Acid Extraction from Laser-Capture Microdissected (LCM) FFPE Tissues
Resource Type: Application Notes
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Optimized Covaris truXTRAC® FFPE RNA Protocol for Isolating RNA from Laser-Capture Microdissected (LCM) FFPE Tissue for Next Generation Sequencing
Resource Type: Application Notes
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Optimized Protocol for Robust Chromatin Shearing and Immunoprecipitation of Human Pancreatic Islets using the Covaris® Focused-ultrasonicator
Resource Type: Application Notes
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Optimizing a Dual Fixation Protocol to Study Protein Complexes Binding to Chromatin in vivo
Resource Type: Application Notes
Download PDFOptimizing a Dual Fixation Protocol to Study Protein Complexes Binding to Chromatin in vivo
Resource Type: Posters
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Optimizing Sample Fixation and Chromatin Shearing for Improved Sensitivity and Reproducibility of Chromatin Immunoprecipitation
Resource Type: Application Notes
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Pipetting Best Practices for Covaris 96 microTUBE Plate and 8 microTUBE Strip in Automated Liquid Handlers
Resource Type: Application Notes
Download PDFPoster Presentation from ASMS 2020: Standardized Sample preparation Workflows for Clinical Proteomics
Resource Type: Posters
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Preparation of whole body Caenorhabditis elegans extracts for chromatin immunoprecipitation using the Covaris® S220 Focused-ultrasonicator
Resource Type: Application Notes
Download PDFProcedure for a new install USB drivers and Covaris SonoLab Single™ software on a Windows 7 computer
Resource Type: Product Inserts and User Manuals
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Protein Extraction from Yeast: Comparison of the Covaris Adaptive Focused Acoustics®(AFA) Process to Conventional Bead Beating and Probe Sonication
Resource Type: Application Notes
Download PDFProtein Extraction of Non-Candida Yeast using an advanced acoustic technology for MALDI-TOF Identification
Resource Type: Posters
Download PDFProtocol truXTRAC® FFPE total NA (tNA) Ultra Kit – Magnetic Bead (25)
Resource Type: Protocols
Download PDFQuick Start Guide: M220 Focused-ultrasonicator Instrument
Resource Type: Product Inserts and User Manuals
Download PDFR230 Focused-ultrasonicator Setup & Instruction Manual
Resource Type: Product Inserts and User Manuals
Download PDFRebuilding Flow Process Vessel SST 22ml (500362)
Resource Type: Product Inserts and User Manuals
Download PDFRebuilding Flow Process Vessel SST 2ml (500390)
Resource Type: Product Inserts and User Manuals
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Release of Microbial Cells from a Solid Matrix, Cell Lysis, and Shearing of Released Nucleic Acids Performed in a One-Step Procedure
Resource Type: Application Notes
Download PDFRemoving or Installing the Intensifier (PN 500141) on an E-Series System
Resource Type: Product Inserts and User Manuals
Download PDFReplacing the ME220 Particle Filter Element and Gasket
Resource Type: Product Inserts and User Manuals
Download PDFReplacing the ME220 Quick Disconnect Insert
Resource Type: Product Inserts and User Manuals
Download PDFReproducible & Automated Sample Preparation for Clinical Proteomics with Focused-ultrasonication
Resource Type: Videos
View VideoReproducible, Hands-free Protein Sample Preparation with Covaris AFA – HUPO Connect 2020
Resource Type: Videos
View VideoRobust pre-analytical sample preparation process preserves the accuracy and fidelity of protein phosphorylation states
Resource Type: Posters
Download PDFRobust Sample Preparation for Label-free or Tandem Mass Tag (TMT) LC-MS with Adaptive Focused Acoustics® (AFA®)
Resource Type: Application Notes
Download PDFRobust Sample Preparation Workflows for Every Analyte from FFPE Samples
Resource Type: Posters
Download PDFS-Series Flow Vessels Adapter Kit (500392)
Resource Type: Product Inserts and User Manuals
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Safety Data Sheet 1x Unsheared DNA – Test Sample; 1x Sheared DNA – Reference Sample
Resource Type: Safety Data Sheets
Download PDFSafety Data Sheet 2X IP Dilution Buffer 3X IP Dilution Buffer US
Resource Type: Safety Data Sheets
Download PDFSafety Data Sheet BB2 Buffer US
Resource Type: Safety Data Sheets
Safety Data Sheet Native Protein Extraction Buffer N EU
Resource Type: Safety Data Sheets
Download PDFSafety Data Sheet Native Protein Extraction Buffer N US
Resource Type: Safety Data Sheets
Download PDFSafety Data Sheet Propylene Glycol for Polyscience Chillers
Resource Type: Safety Data Sheets
Download PDFSafety Data Sheet Protease Inhibitor Cocktail (Tablet) EU
Resource Type: Safety Data Sheets
Download PDFSafety Data Sheet Protease Inhibitor Cocktail (Tablet) US
Resource Type: Safety Data Sheets
Download PDFSafety Data Sheet RNA Elution Buffer EU
Resource Type: Safety Data Sheets
Safety Data Sheet WB4 Buffer EU
Resource Type: Safety Data Sheets
Sample Preparation for Protein Analysis Workflows with AFA Technology
Resource Type: Videos
View VideoScalable FFPE Sample Preparation Method for Clinical Proteomics LC-MS Assays
Resource Type: Posters
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Shearing DNA with Confidence: A Robust Method for Generating 3 kb DNA
Resource Type: Application Notes
Download PDFSimplifying ChIP from Primary Cells and Clinical Samples for Epigenetic Applications
Resource Type: Videos
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Simplifying ChIP from Primary Cells and Clinical Samples for High-throughput Epigenetic Applications
Resource Type: Application Notes
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SOFTWARE INSTALLATION VIA COVARIS WEBSITE
Resource Type: Product Inserts and User Manuals
Download PDFSponge Station & Automation Downholder Universal V2 Mounting Instructions
Resource Type: Product Inserts and User Manuals
Download PDFStandardization of the ChIP Workflow Using Covaris Adaptive Focused Acoustics® (AFA)®
Resource Type: Videos
View VideoStandardize clinical workflows for both WGS and WES with Covaris Adaptive Focused Acoustics® (AFA®)
Resource Type: Videos
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Streamlined FFPE Proteomics with Covaris AFA® and ProtiFi™ S-Trap™ Technologies
Resource Type: Brochures
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Streamlined Ultra Low Sample Input and Processing Volume Chromatin Shearing Protocols for Fly Embryos and Mammalian Cell Lines
Resource Type: Application Notes
Download PDFThe ORIEN Project- Large Scale Integration of FFPE Material into a Multisite Research Alliance
Resource Type: Videos
View VideoThe use of focused acoustics to enhance HTS and STAT immunodiagnostic assays
Resource Type: Posters
Download PDFThe Yin-Yang of Sample Preparation: Reagent optimization for maximal yield, activity, and preservation of biomarkers using Adaptive Focused Acoustics®(AFA®)
Resource Type: Posters
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Tissue Extraction Workflows for Clinical Applications Using cryoPREP® Dry Pulverization
Resource Type: Brochures
Download PDFTissue processing with the CP02 cryoPREP® Automated Dry Pulverizer
Resource Type: Protocols
Download PDFtissueTUBEs and Plugs (TT1, TT1-XT and TT1-P)
Resource Type: Product Inserts and User Manuals
Download PDFtissueTUBEs for Small Samples (TT05, TT05M, TT05 XT and TT05M-XT)
Resource Type: Product Inserts and User Manuals
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Transitioning from custom amplicon-based parallel sequencing to hybrid capture-based sequencing in molecular pathology routine diagnostics
Resource Type: Application Notes
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truCOLLECT® – Blood: A Novel Whole Blood Collection, Preservation and Biomarker Extraction System
Resource Type: Posters
Download PDFtruPREP™: Importance of Ligation in Biotechnology and Molecular Biology
Resource Type: Application Notes
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truXTRAC® FFPE RNA Extraction and Purification – Quality Metrics for Clinical Applications Powered by Adaptive Focused Acoustics® (AFA®)
Resource Type: Application Notes
Download PDFtruXTRAC® FFPE total NA (tNA) Kit – Magnetic Bead Purification (25)
Resource Type: Protocols
Download PDFtruXTRAC® FFPE total NA (tNA) Ultra Kit – Magnetic Bead (25) – KingFisher™ Duo Prime Purification System
Resource Type: Protocols
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truXTRAC® FFPE total Nucleic Acid Plus Kit – Magnetic Beads (Experienced User Guide)
Resource Type: Protocols
Download PDFtruXTRAC® FFPE total NA (tNA) Kit – Magnetic Bead Purification (25)
Resource Type: Protocols
Download PDFtruXTRAC® FFPE total NA Kit – KingFisher™ Duo Prime Purification (25)
Resource Type: Protocols
Download PDFtruXTRAC™ FFPE DNA 8 microTUBE Strip Kit for chemagen Technology (96)
Resource Type: Protocols
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Tumor Tissue Evaluation with the Illumina® TruSight™ Oncology 500 (NGS) Assay using the Covaris R230 Focused-ultrasonicator for Clinical Research Studies
Resource Type: Application Notes
Download PDFUniversal Sample Processing Of Multiple Sample Types For Reproducible Proteomic Sample Preparation
Resource Type: Posters
Download PDFUpgrading to SonoLab version 7.3 for E/LE220 Systems
Resource Type: Product Inserts and User Manuals
Download PDFUtilization of the Covaris® 96 oneTUBE-10 AFA Plate Streamlines NGS Sample Prep
Resource Type: Posters
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Variability in DNA Fragment Size and Distribution Analysis Across Various Fragment Analyzers
Resource Type: Application Notes
Download PDFWCS™ Water Conditioning System User Manual
Resource Type: Product Inserts and User Manuals
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- PRODUCT TYPE Kits & Reagents Remove This Item
- Instrument Compatibility ML230 Remove This Item
- truXTRAC FFPE total NA Ultra Kit – Magnetic Beads
The truXTRAC® FFPE tNA Ultra Kit –Magnetic Beads features the new AFA-TUBE PP Screw-Cap 0.5 ml. This kit contains the reagents and consumables......
SKU : 520304
- FFPE Extraction
1 Item

A Comparison of Active and Passive FFPE DNA Extraction Methods and Effects on Downstream Analysis Metrics
Resource Type: Application Notes
Download PDFA New Effective Method for the Disruption of Pseudomonas aeruginosa Biofilms Using Adaptive Focused Acoustics™(AFA)
Resource Type: Posters
Download PDFA New Workflow for Small Tissue Sample Preparation: Freeze, Fracture, and Extract
Resource Type: Posters
Download PDFA Novel Automated, High Throughput, Plasma Protein Biomarker Enrichment Protocol
Resource Type: Videos
View VideoA Novel Solution to FFPE Extraction Challenges for Downstream Clinical Assays
Resource Type: Videos
View VideoA Paradigm Shift: Desiccated Stabilized Transport System for Viral Specimen Collection
Resource Type: Brochures
Download PDFA Robust and Scalable Workflow for Extraction of DNA, RNA, and Protein from FFPE Tissues
Resource Type: Posters
Download PDFA Robust and Standardized Workflow to Analyze C. albicans Differential Protein Expression using Tandem Mass Tag (TMT)
Resource Type: Application Notes
Download PDFA Robust LC-MS analysis of C. albicans – Differential Protein Expression using AFA focused ultrasonication, SP3 and TMT labelling
Resource Type: Posters
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A Streamlined Workflow to Perform ChIP from FFPE Samples
Resource Type: Application Notes
Download PDFAccurate and Cost-Effective Discovery of Active Gene Regulatory Interactions using Arima-HiChiP
Resource Type: Posters
Download PDFActive Deparaffinization Drives Superior Yields, Quality and Sequencing Coverage from FFPE Tissue Samples
Resource Type: Posters
Download PDF
Active Extraction of Native Proteins from Yeast using Covaris Adaptive Focused Acoustics® (AFA®)
Resource Type: Application Notes
Download PDFActive organic solvent-free paraffin removal is the key to efficient extraction of NGSquality DNA and RNA from FFPE tissues
Resource Type: Posters
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Active paraffin removal from FFPE tissues with Adaptive Focused Acoustics
Resource Type: Application Notes
Download PDFAdaptive focused acoustic lysis for high-throughput shotgun metagenomics and proximity ligation
Resource Type: Posters
Download PDFAdaptive Focused Acoustics: The One Solution for all shearing needs
Resource Type: Posters
Download PDFAdvanced Toolkits for Multiomics
Resource Type: Posters

AFA ultraCUBE Water Management System USER MANUAL
Resource Type: Product Inserts and User Manuals
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AFA-based Efficient DNA Extraction and Optional Mechanical Shearing from Mycobacteria smegmatis
Resource Type: Application Notes
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AFA-based MALDI Biotyper Sample Preparation for Mycobacteria Colonies
Resource Type: Application Notes
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AFA-based MALDI Biotyper™ Sample Prep for MGIT™ Positive Mycobacteria Cultures
Resource Type: Application Notes
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AFA-based Sputum Liquification to Enable Downstream Microbial Analysis
Resource Type: Application Notes
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AFA-energetics®-Mediated DNA Extraction from Yeast and Bacteria Using Scanning in a Labcyte 384-well Plate
Resource Type: Application Notes
Download PDFAFA-Nanocrystal™ Production: Batch-scale (2mL) Cinnarizine (CNZ) Preparation Protocol
Resource Type: Protocols
Download PDFAFA-Nanocrystal™ Production: Batch-scale (2mL) Felodipine Preparation Protocol
Resource Type: Protocols
Download PDFAFA-Nanocrystal™ Production: Batch-scale (2mL) Indomethacin Preparation Protocol
Resource Type: Protocols
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AFA-Nanoemulsion™ : Rice Bran Oil in Water Continuous Process Stream 2 mL Process Vessel
Resource Type: Protocols
Download PDFAFA-Nanoemulsion™ : Rice Bran Oil in Water Continuous Process Stream 22mL Process Vessel
Resource Type: Protocols
Download PDFAFA-sonication Followed by Modified Protein Aggregation Capture (APAC) Enables Direct, Reproducible and Non-toxic Sample Preparation of FFPE Tissue for Mass Spectrometry-based Proteomics
Resource Type: Application Notes
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AFA-TUBE™ The Family of AFA Consumables Designed for Higher Throughput Automation
Resource Type: Brochures
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Affinity-based Enrichment Analyses of DNA Methylation MCIp, MeDIP, hMeDIP
Resource Type: Application Notes
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Amplicon Shearing Using a Covaris® Focused-ultrasonicator
Resource Type: Application Notes
Download PDFAn Automated High-throughput ChIP-Seq Workflow using Covaris Adaptive Focused Acoustics® (AFA®) System for Accelerated IP
Resource Type: Posters
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An Effect of a Shearing Process on the Re-Sequencing of the Arabidopsis thaliana Genome
Resource Type: Application Notes
Download PDFAn optimized single tube workflow for robust, low input NGS library preparation
Resource Type: Posters
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Analysis of DNA fragments using the Agilent 2100 Bioanalyzer
Resource Type: Application Notes
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Assessing FFPE DNA Quality: The “Illumina FFPE QC Kit” Enables Quantitation of Improvements in FFPE DNA Extraction Technologies
Resource Type: Application Notes
Download PDFAutomated Clinical Rapid Whole Exome Sequencing with the Covaris R230 Focused-ultrasonicator
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Automated NGS Library Construction with Eppendorf epMotion® 5075t/TMX and Covaris® Focused-ultrasonicators
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Automated NGS Library Preparation with Beckman Biomek FXP and Covaris E220
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Download PDFAutomated Protein Extraction from Clinical Samples with the Covaris ML230 Focused-ultrasonicator
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Download PDFAutomated Sample Preparation Combining Adaptive Focused Acoustics® (AFA®) and Single Pot Solid Phase Sample Preparation (SP3)
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Download PDFAutomated Sample Preparation for Reproducible Proteomics in Biology and the Clinic
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View VideoAutomated Single Vessel DNA Sample Standardization, Fragmentation, and Library Prep
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CH05 Chiller and AFA ultraCUBE Water Hose Replacement Warning
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Chromatin Interaction Analysis by Paired-End Tag Sequencing – ChIA-PET
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Chromosome Conformation Capture Using Biotinylated Oligos – Capture-C
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Download PDFClinical Tumor Tissue Evaluated with Illumina® TruSight™ Oncology 500 (NGS) Assay and Sheared on the Covaris ML230 Focused-ultrasonicator
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Download PDFCo-extraction of RNA and DNA by Covaris Adaptive Focused Acoustics® (AFA®) Enables Genome-scale Analysis for Most FFPE Tissues
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Combining Covaris 96 AFA-TUBE TPX Plate with Swift Biosciences Accel-NGS 2S Kit for an Optimized Single Tube Workflow for Robust, Low Input NGS Library Preparation
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Comprehensive Sample Preparation for Proteins Enabled by AFA® Technology
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Confidently Profile the Epigenetic Landscape within Archived FFPE Samples using truChIP®
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Download PDFControl Microplate Dynamics with Covaris AFA Mixing and Dissolution
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Covaris Automation Platform Solutions for Pre-analytical Sample Preparation
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Download PDFCovaris cryoPREP® with AFA: Enabling High-resolution Diagnostic Metagenomics
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Covaris DNA shearing guide for the Agilent SureSelect Target Enrichment System©
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Download PDFCovaris DNA Shearing Verification Kit (PN 520120)
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Download PDFCovaris DNA Shearing Verification Kit for AFA-TUBE TPX Consumables (PN 520120)
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Download PDFCovaris DNA Shearing Verification Kit for AFA-TUBE® TPX Plate on the R230
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Download PDFCovaris truChIP– the Next Generation Technology for Chromatin Shearing
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Covaris truSHEAR Mechanical DNA Shearing for NGS Applications
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Covaris truSHEAR™ Precision DNA Shearing Enables Precision Medicine
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Download PDFCovaris Webinar: Optimizing the Extraction of High Molecular Weight DNA from Tissue
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CP01 cryoPREP® Manual Dry Pulverizer User Manual
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Cross-linked Yeast Chromatin shearing on the Covaris E210
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Cross-linked Yeast Chromatin Shearing on the Covaris Focused-ultrasonicator
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cryoPREP® Product Line: The non-contact, rapid, dry pulverization system for biological tissue
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Cytosine Conversion-based, Genome-wide and Targeted DNA Methylation Analysis
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Download PDFDirect, Reproducible and Non-toxic Sample Preparation of FFPE Tissue for MS-based Proteomics
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DNA Extraction from FFPE samples with Covaris Focused-ultrasonicators
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Download PDFDNA Extraction of Lung Cancer Samples for Advanced Diagnostic Testing
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DNA Shearing for Next Generation Sequencing (NGS) with the M220 Focused-ultrasonicator
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Download PDFDNA Shearing Protocols for Ion Torrent Platforms with the M220 Focused-ultrasonicator
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Download PDFDNA Shearing Quick Guide: microTUBE-15 with S220/E220 Focused-ultrasonicator.
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E220 / E220x (E-Series) High Performance Multi-Sample Preparation System
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Download PDFE220 & LE220 (-plus, R-plus, Rsc) Setup & Instruction Manual
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Effective disruption of Pseudomonas aeruginosa biofilms using Adaptive Focused Acoustics® (AFA®)
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Download PDFEfficient Sample Preparation with Covaris AFA® Technology Enhances Confidence in Illumina® TruSight™ Oncology 500 Assay
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Download PDFEnabling Efficiency with Acoustic Energy: High-throughput DNA Shearing
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Download PDFEpigenomics at the Speed of Sound: High-throughput Epigenomic Mapping of Low Cell Input Samples using Acoustic Enhanced Immunoprecipitation
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Download PDFEvaluation of a New Protein Extraction Method Using an Advanced Acoustic Technology for Identification of Filamentous Fungi by MALDI-TOF MS
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Evaluation of Next Generation Library Preparation using DNA Extracted from Dried Blood Spots using truXTRAC® DBS DNA kit
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Download PDFExperienced User Quick Guide: truXTRAC® FFPE total Nucleic Acid Plus Kit – Column
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Download PDFExperienced User Quick Guide: truXTRAC® FFPE total Nucleic Acid Plus Kit –Magnetic Beads
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Download PDFExtraction of RNA from Laser-Capture Microdissected Clinical FFPE Samples
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Five-Minute Ultrasonic Inactivation and Protein Extraction of Mycobacteria for Identification by MALDI-ToF MS
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Download PDFFocused Acoustic Enabled High Quality Extraction of both DNA and RNA and Subsequent Bead Purification from an FFPE Sample
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Focused-ultrasonicators Standardize Sample Preparation for a Variety of Application Areas
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Formaldehyde-Assisted Isolation of Regulatory Elements – FAIRE
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Formulation and Drug Delivery Breakthrough processing for poorly soluble API’s
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Download PDFFour Minute Mycobacterium sp. Sample Preparation Process for MALDI-TOF Identification
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Download PDFFrom Tissues to LC-MS-ready Protein Digests: Automated Sample Preparation Enabled by Adaptive Focused Acoustics® (AFA®) Technology
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Hands-off Sample Preparation Workflow for Laser Capture Microdissection (LCM) Samples using Adaptive Focused Acoustics (AFA)
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High Molecular Weight DNA Extraction and Purification from Whole Blood – Fully-automatable and High-Throughput
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Download PDFHigh Molecular Weight DNA Sample and Library Preparation For Long-Read Sequencing Using Clinical Tissue Specimens
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Download PDFHigh Performance Multiplexed Target Enrichment Sequencing from FFPE Tissues
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Download PDFHigh Quality DNA and RNA Extraction and Purification from FFPE Samples with Covaris truXTRAC® FFPE tNA Ultra Kit – Magnetic Beads
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High Throughput nucleic acid fragmentation for High Throughput next-gen sequencing applications
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Download PDFHigh Throughput processing of Human Cardiomyocytes using Covaris AFA technology
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High-throughput High Molecular Weight DNA Extraction from Human Tissues for Long-read Sequencing
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High-Throughput, Low Volume gDNA Extraction from Whole Blood Enabled by Covaris Adaptive Focused Acoustics® (AFA®) and AFA-TUBE® TPX
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Download PDFHigh-Throughput, Low Volume gDNA Extraction from Whole Blood Enabled by Covaris Adaptive Focused Acoustics® (AFA®) and AFA-TUBE™ TPX
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Download PDFImpact of AFA-energetics™ on Enzymatic Hydrolysis of Proteins
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Download PDFIncorporating Covaris Focused-ultrasonication into a Fully Automated Diagnostic NGS Workcell
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View VideoInline Thermocouple for Flow Cell (500384)
Resource Type: Product Inserts and User Manuals
Download PDFKingFisher™ Duo Prime Purification in combination with the truXTRAC® FFPE total NA Kit
Resource Type: Software
Download PDFKingFisher™ Duo Prime Purification in combination with the truXTRAC® FFPE total NA Plus Kit
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Download PDFKingFisher™ Duo Prime Purification in combination with the truXTRAC® cfDNA Kit
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Download PDFLE220 (-plus, R-plus, and Rsc) Setup & Instruction Manual
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LE220Rsc Focused-ultrasonicator: High-performance, Scalable, Automated Sample Preparation
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Download PDFLoading and Rebuilding Process Vessel SST 2ml (500350) Using Prep-Station (500345)
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Download PDFLoading and Rebuilding Process Vessel SST 300µl (500328) Using Prep Station (500333)
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Download PDFLoading and unloading Process Vessel SST 2ml (500350) onto Holder Process Vessel SST 2ml (500347)
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Download PDFLoading and unloading Process Vessel SST 300µl (500328) onto Holder Process Vessel SST 300µl (500319)
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Lysis and Extraction of Biomolecules from Eukaryotic and Prokaryotic Cells Powered by AFA-energetics®
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Lysis and High Molecular Weight DNA Extraction from Eukaryotic and Prokaryotic Cells Powered by AFA-energetics®
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M220 Focused-ultrasonicator Setup & Instruction Manual
Resource Type: Product Inserts and User Manuals
Download PDFMaintaining SonoLab 7 Log and History Files
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Download PDFMeasuring Sodium Dodecyl Sulfate Carryover In Protein Hydrolysates Prepared via Protein Aggregation Capture
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Download PDFMechanical Fragmentation of RNA using the Covaris Adaptive Focused Acoustics® (AFA®) Technology for Development of mRNA-based Vaccine and Gene Therapy Platforms
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Microbiome Sample Preparation: Efficient DNA Extraction and Optional Mechanical Shearing
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Microbiome Samples: Reveal the Hidden Diversity Using Adaptive Focused Acoustics® (AFA®)
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Download PDFmicroTUBE-50 AFA® Fiber Screw-Cap (PN 520166) Product Insert
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Download PDFML230 Focused-ultrasonicator Uninstallation and Packaging Instructions for Return Shipment
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Download PDFNano-suspension formation via crystallization (Felodipine based)
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Download PDFNGS Quality Sample Preparation with Covaris Adaptive Focused Acoustics (AFA)
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View VideoNovel, Automated Co-extraction of High-quality DNA and RNA from a Single FFPE Sample
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Nucleic Acid Extraction from Laser-Capture Microdissected (LCM) FFPE Tissues
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Optimized Covaris truXTRAC® FFPE RNA Protocol for Isolating RNA from Laser-Capture Microdissected (LCM) FFPE Tissue for Next Generation Sequencing
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Optimized Protocol for Robust Chromatin Shearing and Immunoprecipitation of Human Pancreatic Islets using the Covaris® Focused-ultrasonicator
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Optimizing a Dual Fixation Protocol to Study Protein Complexes Binding to Chromatin in vivo
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Optimizing Sample Fixation and Chromatin Shearing for Improved Sensitivity and Reproducibility of Chromatin Immunoprecipitation
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Pipetting Best Practices for Covaris 96 microTUBE Plate and 8 microTUBE Strip in Automated Liquid Handlers
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Download PDFPoster Presentation from ASMS 2020: Standardized Sample preparation Workflows for Clinical Proteomics
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Preparation of whole body Caenorhabditis elegans extracts for chromatin immunoprecipitation using the Covaris® S220 Focused-ultrasonicator
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Download PDFProcedure for a new install USB drivers and Covaris SonoLab Single™ software on a Windows 7 computer
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Protein Extraction from Yeast: Comparison of the Covaris Adaptive Focused Acoustics®(AFA) Process to Conventional Bead Beating and Probe Sonication
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Download PDFProtein Extraction of Non-Candida Yeast using an advanced acoustic technology for MALDI-TOF Identification
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Download PDFProtocol truXTRAC® FFPE total NA (tNA) Ultra Kit – Magnetic Bead (25)
Resource Type: Protocols
Download PDFQuick Start Guide: M220 Focused-ultrasonicator Instrument
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Download PDFR230 Focused-ultrasonicator Setup & Instruction Manual
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Download PDFRebuilding Flow Process Vessel SST 22ml (500362)
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Download PDFRebuilding Flow Process Vessel SST 2ml (500390)
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Release of Microbial Cells from a Solid Matrix, Cell Lysis, and Shearing of Released Nucleic Acids Performed in a One-Step Procedure
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Download PDFRemoving or Installing the Intensifier (PN 500141) on an E-Series System
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Download PDFReplacing the ME220 Particle Filter Element and Gasket
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Download PDFReplacing the ME220 Quick Disconnect Insert
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Download PDFReproducible & Automated Sample Preparation for Clinical Proteomics with Focused-ultrasonication
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View VideoReproducible, Hands-free Protein Sample Preparation with Covaris AFA – HUPO Connect 2020
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View VideoRobust pre-analytical sample preparation process preserves the accuracy and fidelity of protein phosphorylation states
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Download PDFRobust Sample Preparation for Label-free or Tandem Mass Tag (TMT) LC-MS with Adaptive Focused Acoustics® (AFA®)
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Download PDFRobust Sample Preparation Workflows for Every Analyte from FFPE Samples
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Download PDFS-Series Flow Vessels Adapter Kit (500392)
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Safety Data Sheet 1x Unsheared DNA – Test Sample; 1x Sheared DNA – Reference Sample
Resource Type: Safety Data Sheets
Download PDFSafety Data Sheet 2X IP Dilution Buffer 3X IP Dilution Buffer US
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Download PDFSafety Data Sheet BB2 Buffer US
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Safety Data Sheet Native Protein Extraction Buffer N EU
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Download PDFSafety Data Sheet Native Protein Extraction Buffer N US
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Download PDFSafety Data Sheet Propylene Glycol for Polyscience Chillers
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Download PDFSafety Data Sheet Protease Inhibitor Cocktail (Tablet) EU
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Download PDFSafety Data Sheet Protease Inhibitor Cocktail (Tablet) US
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Download PDFSafety Data Sheet RNA Elution Buffer EU
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Safety Data Sheet WB4 Buffer EU
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Sample Preparation for Protein Analysis Workflows with AFA Technology
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View VideoScalable FFPE Sample Preparation Method for Clinical Proteomics LC-MS Assays
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Shearing DNA with Confidence: A Robust Method for Generating 3 kb DNA
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Download PDFSimplifying ChIP from Primary Cells and Clinical Samples for Epigenetic Applications
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Simplifying ChIP from Primary Cells and Clinical Samples for High-throughput Epigenetic Applications
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SOFTWARE INSTALLATION VIA COVARIS WEBSITE
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Download PDFSponge Station & Automation Downholder Universal V2 Mounting Instructions
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Download PDFStandardization of the ChIP Workflow Using Covaris Adaptive Focused Acoustics® (AFA)®
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View VideoStandardize clinical workflows for both WGS and WES with Covaris Adaptive Focused Acoustics® (AFA®)
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Streamlined FFPE Proteomics with Covaris AFA® and ProtiFi™ S-Trap™ Technologies
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Streamlined Ultra Low Sample Input and Processing Volume Chromatin Shearing Protocols for Fly Embryos and Mammalian Cell Lines
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Download PDFThe ORIEN Project- Large Scale Integration of FFPE Material into a Multisite Research Alliance
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View VideoThe use of focused acoustics to enhance HTS and STAT immunodiagnostic assays
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Download PDFThe Yin-Yang of Sample Preparation: Reagent optimization for maximal yield, activity, and preservation of biomarkers using Adaptive Focused Acoustics®(AFA®)
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Tissue Extraction Workflows for Clinical Applications Using cryoPREP® Dry Pulverization
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Download PDFTissue processing with the CP02 cryoPREP® Automated Dry Pulverizer
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Download PDFtissueTUBEs and Plugs (TT1, TT1-XT and TT1-P)
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Download PDFtissueTUBEs for Small Samples (TT05, TT05M, TT05 XT and TT05M-XT)
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Transitioning from custom amplicon-based parallel sequencing to hybrid capture-based sequencing in molecular pathology routine diagnostics
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truCOLLECT® – Blood: A Novel Whole Blood Collection, Preservation and Biomarker Extraction System
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Download PDFtruPREP™: Importance of Ligation in Biotechnology and Molecular Biology
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truXTRAC® FFPE RNA Extraction and Purification – Quality Metrics for Clinical Applications Powered by Adaptive Focused Acoustics® (AFA®)
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Download PDFtruXTRAC® FFPE total NA (tNA) Kit – Magnetic Bead Purification (25)
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Download PDFtruXTRAC® FFPE total NA (tNA) Ultra Kit – Magnetic Bead (25) – KingFisher™ Duo Prime Purification System
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truXTRAC® FFPE total Nucleic Acid Plus Kit – Magnetic Beads (Experienced User Guide)
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Download PDFtruXTRAC® FFPE total NA (tNA) Kit – Magnetic Bead Purification (25)
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Download PDFtruXTRAC® FFPE total NA Kit – KingFisher™ Duo Prime Purification (25)
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Download PDFtruXTRAC™ FFPE DNA 8 microTUBE Strip Kit for chemagen Technology (96)
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Tumor Tissue Evaluation with the Illumina® TruSight™ Oncology 500 (NGS) Assay using the Covaris R230 Focused-ultrasonicator for Clinical Research Studies
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Download PDFUniversal Sample Processing Of Multiple Sample Types For Reproducible Proteomic Sample Preparation
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Download PDFUpgrading to SonoLab version 7.3 for E/LE220 Systems
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Download PDFUtilization of the Covaris® 96 oneTUBE-10 AFA Plate Streamlines NGS Sample Prep
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Variability in DNA Fragment Size and Distribution Analysis Across Various Fragment Analyzers
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Download PDFWCS™ Water Conditioning System User Manual
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